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1.
Severe Acute Respiratory Syndrome Coronavirus 2 Antibodies in Adults in Madrid, Spain.
Soriano, Vicente; Meiriño, Rosa; Corral, Octavio; Guallar, María Pilar.
Clin Infect Dis ; 72(6): 1101-1102, 2021 03 15.
Article in English | MEDLINE | ID: covidwho-1147252

Subject(s)
COVID-19 , Pandemics , Adult , Humans , Public Health , SARS-CoV-2 , Spain/epidemiology
2.
Inoculum at the time of SARS-CoV-2 exposure and risk of disease severity.
Guallar, María Pilar; Meiriño, Rosa; Donat-Vargas, Carolina; Corral, Octavio; Jouvé, Nicolás; Soriano, Vicente.
Int J Infect Dis ; 97: 290-292, 2020 Aug.
Article in English | MEDLINE | ID: covidwho-597415

ABSTRACT

A relationship between the infecting dose and the risk of disease severity has not been demonstrated for SARS-CoV-2 infection. Here, we report three clusters of individuals that were potentially exposed to distinct inoculum in Madrid. Overall each group developed divergent clinical forms of COVID-19. Our data support that a greater viral inoculum at the time of SARS-CoV-2 exposure might determine a higher risk of severe COVID-19.


Subject(s)
Coronavirus Infections/transmission , Pneumonia, Viral/transmission , Viral Load , Adult , Aged , Aged, 80 and over , Betacoronavirus , COVID-19 , Coronavirus Infections/epidemiology , Female , Humans , Male , Middle Aged , Pandemics , Pneumonia, Viral/epidemiology , SARS-CoV-2 , Spain/epidemiology , Time Factors , Virulence
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